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KMID : 1103920080140020206
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Korean Journal of Hepatology
2008 Volume.14 No. 2 p.206 ~ p.212
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Four cases of toxic Liver injury associated with Dictamnus dasycarpus
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Jang Jong-Soon
Wang Joon-Ho
Lee Jae-Dong
Kim Soon-Je
Hahn Zhe
Chae Hee-Bok
Seo Eui-Keun
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Abstract
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We report four cases of toxic hepatitis that occurred after taking a decoction made by boiling down the root of Dictamnus dasycarpus. The four patients had a median age of 60 years, common symptoms of jaundice and general weakness, and stated that they had not consumed alcohol for at least 5 years. The markers of hepatitis A, B, and C were all negative in the patients. Abdominal ultrasonography revealed common bile ducts with normal diameters. Two of the cases were a mother and daughter, and the other two were sporadic. All of them had consumed a decoction made by boiling down the root of Dictamnus dasycarpus five or six times daily until several days before admission. Dictamnus dasycarpus induced liver injury presenting with a benign course lasting less than 1 month after cessation of the causative agent. We suggest that this natural product can cause acute hepatitis in rural areas.
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KEYWORD
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Dictamnusdasycarpus, Herbalmedicine, ToxicLiverinjury
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